マトリキシルとは？
マトリキシルは、肌の自然な再生プロセスを活用する有効成分のシリーズです。これらの生体模倣ペプチドは、コラーゲン、エラスチン、ヒアルロン酸といった肌の構成要素の生成を促進し、その結果、科学的に証明されたアンチエイジング効果をもたらします。
Croda Beauty Actives（当時はセダーマ社として知られていました）は、2000年抗シワに特化した世界初のマトリカイン®（細胞外マトリックス由来ペプチド）を発売しました。私たちはそれをマトリキシルと名付けました。
現在、マトリキシルシリーズには4種類のペプチドがあり、処方やCSRのニーズに応じていくつかのバージョンがあります。
すべてのマトリキシル成分は、研究室での皮膚細胞に対する厳格な試験と、数百人ものボランティアを対象とした安全な臨床試験を行っています。
これらの広範な試験により、当社の科学者はマトリキシルシリーズのペプチドがどのように機能するかを正確に判断し、それらがもたらす目に見えるアンチエイジング効果を明確に示すことができます。
Five benefits of Matrixyl
Trusted by thousands of cosmetic professionals and consumers worldwide, Matrixyl is safe, reliable and it works.
５つの特長の詳細
Trust in Matrixyl
Hear what scientists, dermatologists and consumers have to say about award-winning Matrixyl
Independent research shows Matrixyl works
‘Our research, shows that products with Matrixyl will have skin-care benefits.’
Professor Ian Hamley, from the University of Reading's Department of Chemistry
During their studies, the University of Reading researchers measured the effectiveness of Matrixyl on collagen. They found that Matrixyl can almost double the amount of collagen that the cells in our body produce, provided the concentration is high enough.
The research that produced the results above was supported by a university studentship with additional funding by the Engineering and Physical Sciences Research Council (EPSRC).
Recognition from our peers
Dr Jenna Queller, Beverley Hills
"Matrixyl is the most popular peptide for cosmetic use (…) effective in improving the appearance of fine lines"
Dr Emma Wedgeworth, London
"Matrixyl is a promising ingredient because it is a small molecule which helps to stimulate collagen within the skin… The newer sister molecule Matrixyl 3000, contains two newer peptides, which are thought to be even more effective then the original."
Dr Bell, Nottingham
"The peptide blend of Matrixyl 3000+ in the Line Correcting Booster Serum is an ideal targeted solution for lines as it stimulates the collagen and elastin that is lost early on in the ageing process."
Dr Nick Lowe, London
"Matrixyl (…) reduces the breakdown of collagen and stimulates the production of new collagen in the skin too, making it look smoother and together."
Matrixyl in the spotlight
“Anti-wrinkle creams that really work... but only with a magic ingredient”. Read story
"Stand by for the frenzy": Scientists find 'miracle' anti-wrinkle ingredient in face creams DOES work”. Read story
“Scientists Find 'Miracle Ingredient' In Anti-Wrinkle Creams”. Read story
“Matrixyl™ has a special place among key cosmetic ingredients. Here is its story.” Read story
Trust building
"I'm quite a big fan the Matrixyl® smooths over my skin beautifully and then dries quickly. After about 3 weeks my face is plumping out which is making my wrinkles appear less and the Hyaluronic Moisturiser certainly compliments the Matrixyl®."
"Matrixyl® Synthe 6® is so light and my skin just drinks it up! It doesn't feel oily at all, I feel like this product has most certainly helped my goal to turn back time! I've been using it for about a year and I love it!"
"I ordered 2 dermarollers and Matrixyl® 3000. Superior product. Just a drop or 2 of the matrixyl covers all area. I'll be using these rollers for a very long time because the quality is superb."
"I started using this Synthe6® regularly for the last 30 days and have already noticed improvement in my crow's feet. This product is really amazing. Goodbye Botox."
Ethically produced
Although synthetic in origin, the ingredients used in Matrixyl feature a very good natural index:
- Matrixyl: 25% natural content* / 78.49% natural origin content*
- Matrixyl 3000: 25% natural content* / 78.49% natural origin content*
- Matrixyl 3000 Glyx (an alternative greener version of Matrixyl 3000): 23.2% naturel content*/ 99.99% natural origin content*
- Matrixyl synthe'6: 20% natural content* / 99.8% natural origin content*
- Matrixyl Morphomics: 95.75% natural content* / 99.79% natural origin content*
To increase their bioavailability and ensure effective reach to their targeted cells, Matrixyl ingredients are palmitoylated. All of them are certified according to the RSPO Supply Chain Certification Standard (Roundtable on Sustainable Palm Oil).
*Values are provided according to our interpretation of the standard ISO 16128. They are likely to evolve in line with discussions within professional federations of the cosmetic industry.
MATRIKINES, the key to anti-ageing
In 1999, the French Professor, François-Xavier Maquart and his team published their first article mentioning Matrikine (1) .
Matrikines are peptides, derived from the surrounding extracellular matrix. These particular peptides act like messengers to other cells, that start the repair process within the tissue matrix, hence the name.
When a Matrikine peptide is recognised by a cell membrane receptor and binds to that receptor, it triggers intracellular action that:
- Promotes tissue repair
- Helps with wound healing
- Stimulates macromolecule synthesis
Since 1999, a huge number of different Matrikines have been identified. Some with very specialised functions like the stimulation of collagen and fibronectin synthesis in the skin.
These are the kind of peptides Sederma has been developing for their anti-ageing properties. It’s these Matrikines you’ll find in the Matrixyl range
(1) MAQUART FX. et al, 1999, Régulation de l’activité cellulaire par la matrice extracellulaire : le concept de Matrikines, Journal de la Société de Biologie, 193, (4), p 423.